Some rhyme and reason.
Big East- Georgetown (playing for #1 seed should motivate them). Louisville is too, but I think they fall short
Big 12 (10)- Kansas
Big 10 (12)- Indiana
ACC- NC State. They could lose their 1st game as well. A feeling on that one.
MWC- San Diego St
Top 4 seeds (in order): Indiana, Georgetown, Duke, Gonzaga